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ScCdd1 Cytidine Deaminase
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PDB entries:
  apo Tetramer 1R5T 
The Leadzyme Ribozyme
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PDB entries:
  24-mer (MgII) 1NUJ
24-mer (MgII + SrII) 1NUV

NNA7 Fab Fragment
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PDB entries:
'wild type'
(MES buffer) 1T2Q
mutant (Gly91Ser/MES buffer) 2D03
Ornithine Cyclodeaminase
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PDB entries:
dimer (NAD+ & ornithine) 17XD
dimer (NAD+) 1U7H
The Hairpin Ribozyme
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PDB entries:
 64-mer mA-1 1X9K
61-mer (mA-1/U39C) 1X9C
61-mer (mA-1/U39/altU37) 2D2K
61-mer (mA-1/propyl39) 2D2I
61-mer (mA-1/U39C) 2OUE
61-mer (mA-1/G8I/U39C) 1ZFT
61-mer (rA-1/G8A/U39C) 1ZFV
61-mer (rA-1/G8U/U39C) 1ZFX
61-mer (rA-1/AP8/U39C) 2BCY
61-mer (dA-1/G8I/U39C) 2BCZ
61-mer (rA-1/G8DAP/U39C) 2FGP
61-mer (2aminoU-1/U39C/S914) 2NPY
61-mer (dA-1/U39C/propyl14) 2NPZ
61-mer (mA-1/U39C/S914/product mimic) 2P7D
61-mer (mA-1/U39C/S914/vanadate TS mimic) 2P7E
61-mer (mA-1/U39C/S914/2'-5' reaction int. mimic) 2P7F
61-mer (2'-5'/U39C/S914/A38G) 3B58
61-mer (2'-5'/U39C/S914/A38DAP) 3B5F
61-mer (2'-5'/U39C/S914/A38AP) 3B91
61-mer (2'-5'/U39C/S914/A38C) 3BBK
61-mer (mA-1/U39C/S914/A38G) 3B5A
61-mer (mA-1/U39C/S914/A38DAP) 3B5S
61-mer (mA-1/U39C/S914/A38AP) 3BBI
61-mer (mA-1/U39C/S914/A38C) 3BBM














HIV-1 Protease
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PDB entries:
dimer (inhibitor GRL06579
) 2HB3

APOBEC3G SAXS Envelope
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Welcome to the Wedekind Lab Web Site.

Our lab uses X-ray diffraction methods to investigate the structures of protein and RNA enzymes. The goal of this research is to elucidate the mechanism of action of these molecules at the molecular level. Other techniques employed include: small angle X-ray scattering (SAXS), comparative modeling, single- and multi-turnover kinetics, organic synthesis of novel nucleosides,
circular dichroism spectroscopy, molecular biological techniques , HPLC and dynamic light scattering.

Click a link to the left to find out more about us and what we do.


Last update: 02/04/08 (JEW)
For comments, questions, etc. please visit the contact page

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