Course Information

Crystallography Learning Links
BCH/IND 408
BPH 411/CHM 402
BCH 412
BCH 510 RIT Lectures 2006

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Crystallography Learning Links

Especially useful for BCH 412 and BPH 411

    Additional Resources:
  1. Young's double slit experiment: vsg.quasihome.com/interf.htm
  2. Constructive and destructive interference: www.colorado.edu/physics/2000/applets/fourier.html
  3. Bragg's Law applet: www.eserc.stonybrook.edu/ProjectJava/Bragg
  4. Fourier approximations: www.jhu.edu/~signals
  5. Miller indices and Bragg planes: www.ysbl.york.ac.uk/~cowtan/sfapplet/frame_miller.html
  6. Randy Read at the M.R.C.: www-structmed.cimr.cam.ac.uk/course.html
  7. Central Limit Theorem: www.math.csusb.edu/faculty/stanton/probstat/clt.html
  8. Anomalous Scattering: www.bmsc.washington.edu/scatter/

BCH/IND 408: Biochemistry

Fall 2003

  1. X-Ray Crystallography Part I (9/15/03)
  2. X-Ray Crystallography Part II (9/17/03)
  3. Workshop Paper for Wednesday/Thursday (9-17 and 9-18)
  4. “High Resolution Structure of the Large Ribosomal Subunit from a Mesophilic Eubacterium” by Harms et al., and Yonath (2001) Cell 107, 679-688.
  5. Assignment: Read the paper and answer the questions on page 30 of lecture II

BPH 411/CHM 402: Methods of Structural Biology

Spring 2006 (See also Crystallography Learning Links above)

  1. Lecture 01 (2/09/06)
  2. Lecture 02 (2/14/06)
  3. Lecture 03 (2/16/06)
  4. Lecture 04 (2/21/06)
  5. Lecture 05 (2/23/06)
  6. Lecture 06 (2/23/06)
  7. Lecture 07 (2/28/06)
    Additional Material:
  1. 2004 Wedekind midterm section: Exam
  2. 2006 Wedekind midterm section: Exam

BCH 412: Advanced Topics in Biological Macromolecules

Spring 2006 (See also Crystallography Learning Links above)

  1. Crystallography Part I (2/27/06)
  2. Crystallography Part II (3/01/06)
  3. Crystallography Part III (3/03/06)
  4. Crystallography Appendix II (3/01/06)
    Additional Material:
  1. 2004 Wedekind homework: Answer key

BCH 510: Enzyme Mechanisms

Fall 2004

  1. The Chemistry of Phosphoryl Transfer: Ribozyme Catalysis (10/04/04)

RIT Lectures

Spring 2006

    Lecture Notes:
  1. Principles of X-Ray Crystallography (04/24/06)
    Lysozyme Case Study (with embedded movies of crystal manipulation):
  1. Hen Egg White Lysozyme Workshop (04/24/06)
    Practical Crystallography - A Case of Induced Fit:
  1. Practical Principles of X-Ray Crystallography and a Case Study (04/24/06)
  2. Hexokinase Crystal Structure Showing Induced Fit (T.A. Steitz 1978 Manuscript) (04/24/06)
  3. Small Angle X-ray Scattering (SAXS) of Phosphoglycerate Kinase (T.A. Steitz 1979 Manuscript) (04/24/06)
  4. The 50S Ribosome: A Case of Induced Fit (T.A. Steitz 2005 Manuscript) (04/24/06)

(updated April 2006 ATT)
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