Pearce Lab- Employment Information

Employment Opportunities

POSTDOCTORAL FELLOWSHIP

Center for Neural Development and Disease, University of
Rochester School of Medicine, Rochester, NY.

Postdoctoral positions are available immediately to study of the most common childhood neurological disorder, Batten disease. The specific area's of research are:

1. To study the function of Btn1p in yeast. Btn1p is the yeast homologue to the human Cln3p which when defective is responsible for the most common childhood neurological disorder, Batten disease. We are studying Btn1p with the awesome power of yeast genetics, and have demonstrated that deletion of BTN1 ( btn1- D ) is complemented by human CLN3 (Pearce et al ., 1999 [Nat. Genet., 22, 55-58]). We are looking for a highly motivated individual with experience in yeast molecular biology to contribute to the research and understanding of this devastating disease.

2. Elucidating the contribution of a novel autoimmune response to GAD65 that exists in both individuals with Batten disease, and a mouse model for the disease (Chattopadhyay et al, 2002 [Hum. Mol. Genet. 11, 1421-1431]).

3. Determining the biochemical and pathological cascades that occur in the developing CNS of a mouse model for Batten disease.

We are looking for highly motivated individuals with experience in immunology and molecular biology and molecular neuroscience for each position, respectively, to contribute to the research and understanding of this devastating disease.

For more information please contact:

David A Pearce
Center for Aging and Developmental Biology
Department of Biochemistry and Biophysics
Box 645
University of Rochester School of Medicine
601 Elmwood Avenue
Rochester, NY 14642

Tel: 585 273 1514
FAX: 585 276-1972
E-Mail: David_Pearce@urmc.rochester.edu

Dr. David Pearce

Employment Opportunities

POSTDOCTORAL FELLOWSHIP