Zung Yoon Yang

Education
Aug. 2000 to present	Ph.D Candidate in Pathology Department of Pathology University of Rochester School of Medicine and Dentistry, Rochester, NY
Feb 1993 to Jan. 1995	M.S., Biochemistry and Molecular Biology Hanyang University, Korea
Jan. 1990 to Sept. 1990	1st semester of Master's program, Biochemistry and Molecular Biology Hanyang University, Korea
Feb 1986 to Jan. 1990	B.S., Bioichemistry and molecular Biology Hanyang University, Korea

Research Experience
1998-Present	Department of Pathology, University of Rochester School of Medicine and Dentistry, Rochester, NY Ph.D. Research Advisor: Dr. Jeffrey Hayes Structure and Interactions within a transcription factor IIIA-nucleosome triple complex.
Feb. 1999 to Feb. 2000	Choongwae Pharmaco. Company, Korea Senior Research Scientist, Central Research Center Second leader in New Drug Deveopment Team II Team Leader: Dr. Dalkyun Oh Development of a novel expression system for a high level production of hGH, Interferon-beta, gamma, EPO, TPO.
Jan. 1995 to Jan. 1999	Choongwae Pharmaco. Company, Korea Research Scientist, Central Research Center Team Leader: Dr. Dujong Paik Development of anti-cancer drugs: competitive inhibitors of methylenetetrahydrofolate in thymidylate synthetase.
Feb. 1993 to Jan. 1995	Yonsei University, Korea M.S. Research Advisor: Dr. Youngki Paik Characterization and Purification of a nuclear factor that binds to an upstream regulatory element of the rat apolipoprotein E gene.
Nov. 1990 to Jan. 1993	The 55 ammunition battalion, Korea Sergeant, Military Service Superior: Captain Hoon Kim
Jan. 1990 to Sept. 1990	Hanyang University, Korea M.S. Research Advisor: Dr. Youngki Paik Characterization of an upstream regulatory element of the human apolipoprotein E gene and purification of its binding protein from the human placenta.

Publications

Zungyoon Yang, Jonghwa Lim and Dalkyun Oh. (in preparation) A novel prokaryotic promoter element that promotes high level productions of human growth hormone, erythropoietin, interferon-alpha, Interferon-beta, regardless N-terminal natural coding sequences of the proteins. Junquiang Ye, Zungyoon Yang, Jeffrey J. Hayes and Thomas H. Eickbush. (2002) R2 retrotransposition on assembled nucleosomes depends on the translational position of the target site. The EMBO Journal, 21: 6853-6864 Dujong Paik, Yangki Park, Hongil Heo, Myounghee Lee, Zungyoon Yang and Myounghee Choi. (1998) Synthesis of 5-substituted quinazolinone derivatives and their inhibitory (anti-cancer) activity in vitro. Bioorganic & Medicinal Chemistry Letters, 8: 3287-3290 Daewoong Joe, Trond P. Leren, Zungyoon Yang, Youngho Chung, John, M. Taylor and Youngki Paik. (1995) Characterization of an upstream regulatory element of the human apolipoprotein E gene and purification of its binding protein from the human placenta. J. Biochem., 117: 915-922 Zungyoon Yang, Daewoong Joe and Youngki Paik. Characterization and purification of a nuclear factor that binds to an upstream regulatory element of the rat apolipoprotein E gene. (1994) Korean J. of Lipidology, Volume 2: 135-144.

Patents

Zungyoon Yang, Jonghwa Lim and Dalkyun Oh. (in preparation) A novel expression system for a high level production of hGH. Jaewook Jeong, Soojin Lee, Hyaejin Choi, Sunghwan Moon, Seongjoo Lee, Zungyoon Yang, Jonglyul ha and Donghoon Jeong. The genifin derivatives: anti-viral activity for hepatitis B and anti-cancer, 97-014907, Publication number 98-77684, November 16 1998 Kunhyuk Choi, Doojong Paik, Yangki Park, Hongil Heo, Sungo An, Zungyoon Yang, Mounghee Choi. The quinazolinone derivatives for anti-cancer agents, 97-3035, filing date January 31, 1997.

Presentations and Poster

Zungyoon Yang, J.M. Vitolo, C. Zheng, C. Thiriet, R. Basavappa and J.J. Hayes. Structure and interactions within a transcription factor IIIA-nucleosome triple complex. April 12, 2002. Day in Genetics in University of Rochester. Zungyoon Yang, Mounghee Choi, Hongil Heo, Yangki Park, Sungchan Lee, Sungo An, Hyunjoo Kim and Dujong Paik. CW252 compounds, Folate-based quinazoline derivatives: Thymidylate synthase inhibitory activity and cytotoxicity in vitro. The 46th Annual Convention of the Pharmaceutical Society of Korea, November 1997. Sewoong Oh, Zungyoon Yang, Jongryul Ha and Dujong Paik. In vivo anti-tumor efficacy of CW252053: A novel thymidylate synthase inhibitor, The 46th Annual Convention of the Pharmaceutical Society of Korea, November 1997. Zungyoon Yang, Daewoong Joe and Youngki Paik. Characterization and purification of a nuclear factor that binds to an upstream regulatory element of the rat apolipoprotein E gene. The Annual meeting of the Korean Society for Molecular Biology. October 1994. Zungyoon Yang, Daewoong Joe and Youngki Paik. Characterization of an upstream regulatory element of the human apolipoprotein E gene from the human placenta. The Annual meeting of the Biochemical Society of the Republic of Korea. October 1993.