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Sayura Aoyagi

Sayura Aoyagi
Department of Biochemistry and Biophysics
University of Rochester Medical Center Box 712
Rochester, NY 14642
(585) 275-1706
sayura_aoyagi@urmc.rochester.edu

Education
1998-present Ph.D Candidate in Biochemistry
University of Rochester School of Medicine and Dentistry, Rochester, NY
2001 M.S. in Biochemistry
University of Rochester School of Medicine and Dentistry, Rochester, NY
1998 B.S. with honors in Biochemistry
Trinity College, Hartford, CT

Research Experience
1998-Present Department of Biochemistry and Biophysics, University of Rochester School of Medicine and Dentistry, Rochester, NY
Ph.D. Research
Advisor: Dr. Jeffrey Hayes
Investigation of the Mechanism of Nucleosome Remodeling by ATP-Dependent Chromatin Remodeling Complexes.
1996-1998 Department of Chemistry, Trinity College, Hartford, CT
Honors undergraduate research
Advisor: Dr. Richard Prigodich
Footprinting of E. coli Single-Stranded DNA binding proteins-ssDNA Complex by Capillary Electrophoresis.

Awards and Honors
2002 Elon Huntington Hooker Graduate Fellowship
University of Rochester, Rochester, NY
1998 Phi Beta Kappa
Trinity College, Hartford, CT
1998 American Chemical Society Award, Connecticut Valley Section
Fall 1997 Vernon K. Krieble-Loctite Scholarship (Full Tuition)
Trinity College, Hartford, CT
1997-1998 President’s Fellow in Biochemistry
Trinity College, Hartford, CT

Publications
Fernandez De Henestrosa, A.R., Ogi, T., Aoyagi, S., Chafin, D., Hayes, J.J., Ohmori, H., and Woodgate, R. (2000) Identification of Additional Genes Belonging to the LexA Regulon in Escherichia coli. Mol. Microbiol. 35: 1560-72

Aoyagi, S., Narlikar, G., Zheng, C., Sif, S., Kingston, R.E., and Hayes, J.J. (2002) Nucleosome Remodeling by the Human SWI/SNF Complex Requires Transient Global Disruption Of Histone-DNA Interactions. Mol. Cell. Biol. 22: 3653-3662

Aoyagi, S., and Hayes, J.J. (2002) hSWI/SNF-Catalyzed Nucleosome Sliding Does Not Occur Soley Via a Twist-Diffusion Mechanism. Mol. Cell. Biol. 22: 7484-7490

Huggins, C.F., Chafin, D.R., Aoyagi, S., Henricksen, L.A., Bambara, R.A. and Hayes, J.J. Flap Endonuclease 1 Efficiently Cleaves Base Excision Repair Intermediates Assembled into Nucleosomes. Mol. Cell 10: 1201-1211