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Lab
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Purkayastha S, Milligan JR, Bernhard WA (2008)
An investigation into the mechanisms of DNA strand breakage by direct ionization of variably hydrated plasmid DNA. J Phys Chem B, 112:4152
Swarts SG, Gilbert DC, Sharma KK, Razskazovskiy Y, Purkayastha S, Naumenko KA, Bernhard WA (2007)
Mechanisms of direct radiation damage in DNA, based on a study of the yields of base damage, deoxyribose damage, and trapped radicals in d(GCACGCGTGC)(2). Radiat Res, 168:367-81
Purkayastha S, Milligan JR, Bernhard WA (2007)
On the chemical yield of base lesions, strand breaks, and clustered damage generated in plasmid DNA by the direct effect of X rays. Radiat Res, 168:357-66
Sharma KK, Purkayastha S, Bernhard WA (2007)
Unaltered free base release from d(CGCGCG)2 produced by the direct effect of ionizing radiation at 4 K and room temperature. Radiat Res, 167:501-7
Roginskaya M, Bernhard WA, Razskazovskiy Y (2006)
Protection of DNA against direct radiation damage by complex formation with positively charged polypeptides. Radiat Res, 166:9-18
Purkayastha S, Milligan JR, Bernhard WA (2006)
The role of hydration in the distribution of free radical trapping in directly ionized DNA. Radiat Res, 166:1-8
Purkayastha S, Milligan JR, Bernhard WA (2006)
An investigation into the mechanisms of DNA strand breakage by direct ionization of variably hydrated plasmid DNA. J Phys Chem B Condens Matter Mater Surf Interfaces Biophys, 110:26286-91
Purkayastha S, Milligan JR, Bernhard WA (2005)
Correlation of free radical yields with strand break yields produced in plasmid DNA by the direct effect of ionizing radiation. J Phys Chem B Condens Matter Mater Surf Interfaces Biophys, 109:16967-73
Roginskaya M, Razskazovskiy Y, Bernhard WA (2005)
2-Deoxyribonolactone lesions in X-ray-irradiated DNA: quantitative determination by catalytic 5-methylene-2-furanone release. Angew Chem Int Ed Engl, 44:6210-3
Roginskaya M, Bernhard WA, Marion RT, Razskazovskiy Y (2005)
The release of 5-methylene-2-furanone from irradiated DNA catalyzed by cationic polyamines and divalent metal cations. Radiat Res, 163:85-9
Roginskaya M, Bernhard WA, Razskazovskiy Y (2004) Diffusion approach to long distance charge migration in DNA: time-dependent and steady-state analytical solutions for the product yields. J Phys Chem B, 108:2432-2437 Purkayastha S, Bernhard WA (2004) What is the Initial Chemical Precursor of DNA Strand Breaks Generated by Direct-type Effects?. J Phys Chem B, 108:18377-18382 Bernhard WA, Close DM (2004) DNA damage dictates the biological consequences of ionizing irradiation: the chemical pathways. In: Charged Particle and Photon Interactions with Matter. (Y. Hatano and A. Mozumder), pp. 431-470
Razskazovskiy Y, Debije MG, Howerton SB, Williams LD, Bernhard WA (2003)
Strand breaks in X-irradiated crystalline DNA: alternating CG oligomers. Radiat Res, 160:334-9
Razskazovskiy Y, Debije MG, Bernhard WA (2003)
Strand breaks produced in X-irradiated crystalline DNA: influence of base sequence. Radiat Res, 159:663-9
Debije MG, Close DM, Bernhard WA (2002)
Reductive damage in directly ionized DNA: saturation of the C5=C6 bond of cytosine in d(CGCG)(2) crystals. Radiat Res, 157:235-42
Debije MG, Bernhard WA (2002) Thermally stable sites for electron capture in directly ionized DNA: free radicals produced by the net gain of hydrogen a C5/C6 of cytosine and thymine in crystalline oligodeoxynucleotides. J. Phys. Chem. A, 106:4608-4615 Debije MG, Razskazovskiy Y, Bernhard WA (2001) The yield of strand breaks resulting from direct-type effects in crystalline DNA x-irradiated at 4 K and room temperature. J. Amer. Chem. Soc., 123:2917-2918
Debije MG, Bernhard WA (2001) Electron paramagnetic resonance evidence for a C3' sugar radical in crystalline d(CTCTCGAGAG) x-irradiated at 4 K. Radiat. Res., 155:687-692
Debije MG, Strickler MD, Bernhard WA (2000) On the efficiency of hole and electron transfer from the hydration layer to DNA: An EPR study of crystalline DNA X-irradiated at 4 K. Radiat. Res., 154:163-70
Razskazovskiy Y, Debije MG, Bernhard WA (2000) Direct radiation damage to crystalline DNA: what is the source of unaltered base release? Radiat. Res., 153:436-41
Debije MG, Bernhard WA (1999) Free radical yields in crystalline DNA X-irradiated at 4 K. Radiat. Res., 152:583-9
Milano MT, Bernhard WA (1999) The Influence of Packing on Free Radical Yields in Solid State DNA: Film versus Lyophilized Frozen Solution. Radiat. Res., 152:196-201 Milano MT, Bernhard WA (1999) The Effect of Packing and conformation on Free Radical Yields in Films of Variably Hydrated DNA. Radiat. Res., 151:39-49
Debije MG, Milano MT, Bernhard WA (1999) DNA Responds to Ionizing Radiation as an Insulator, Not as a "Molecular Wire". Angew Chem Int Ed Engl, 38:2752-2756
Milano MT, Hu GG, Williams LD, Bernhard WA (1998) Migration of electrons and holes in crystalline d(CGATCG)-anthracycline complexes X-irradiated at 4 K. Radiat. Res., 150:101-14
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