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2 Information on Yeast

A general introduction to a few selected topics on yeast can be found in the book chapters "Yeast as the E. coli of Eucaryotic Cells" and "Recombinant DNA at Work" (Watson et al., 1987). Comprehensive and excellent reviews of the genetics and molecular biology of S. cerevisiae are contained in three volumes entitled "Molecular Biology of the Yeast Saccharomyces" (Broach et al., 1991; Jones et al., 1992; Pringle et al., 1997). An important source for methods used in genetics and molecular biology of yeast is contained in the book edited by Guthrie and Fink (1991). Overviews of numerous subjects are also covered in other sources (Broach et al., 1991; Brown & Tuite, 1998; Jones et al., 1992; Pringle et al.,1997; Wheals et al., 1995), including protocols applicable to yeasts (Fields & Johnson, 1993) and introductory material (Walker, 1998). A more comprehensive listing of earlier reviews can be found in Sherman (1991). Interesting and amusing accounts of developments in the field are covered in The Early Days of Yeast Genetics (Hall & Linder, 1992). The journal Yeast publishes original research articles, reviews, short communications, sequencing reports, and selective lists of current articles on all aspects of Saccharomyces and other yeast genera.

Current and frequently-updated information and databases on yeast can be conveniently retrieved on the Internet through World Wide Web, including the "Saccharomyces Genomic Information Resource" (http://genome-www.stanford.edu/Saccharomyces/) and linked files containing DNA sequences, lists of genes, home pages of yeast workers, and other useful information concerning yeast. From the MIPS page (http://www.mips.biochem.mpg.de/) you can access the annotated sequence information of the genome of Saccharomyces cerevisiae and view the chromosomes graphically or as text, and more. The YPD page (http://www.proteome.com/YPDhome.html) contains a protein database with emphasis on the physical and functional properties of the yeast proteins.


Send inquiries to: Fred_Sherman@urmc.rochester.edu