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Faculty and their Research

Cell Biology & Immunology

Andrea Bottaro - Antibody Gene Expression and Recombination
Paul Brookes - Mitochrondrial Pathology
John Frelinger - Molecular Immunology
Dave Goldfarb - Nuclear Transport and Autophagy
Fred Hagen - Glycosylation Mechanisms of the Cell
Craig Jordan - Cancer Stem Cells in the Hematopoietic System
Margot Mayer-Proschel - Stem Cells in the CNS
James McGrath - Mechanisms of Actin-Based Motility
Mark Noble - Neural Development and Neoplasia
Dave Pearce - Yeast and Mouse Models for Human Disease
Douglas Portman - Neuronal Development in C. elegans
Charles Thornton - Neurodegenerative Disorders
Yisang Yoon - Regulation of Mitochondrial Dynamics

(NOTE: Additional Cell Biological Research is conducted in the Cellular and Molecular Basis of Medicine Cluster)

DNA Replication, Repair & Recombination

Robert Bambara - Human and HIV DNA Replication
Tom Eickbush - Retrotransposable Elements
Elaine Sia - Mutagenesis and Repair of Mitochondrial DNA

Gene Regulation

Xin Bi - Chromatin Regulation of Gene Expression in Eukaryotes
Mike Bulger - Chromatin Domains and Enhancer Activation
Marty Gorovsky - Chromatin and Transcription
Jeff Hayes - Chromatin Structure
Rulang Jiang - Molecular Genetics of Craniofacial Development
Fred Sherman - Yeast Gene Regulation

Protein Structure & Function

Phil Fay - Blood Clotting Cascade

RNA Structure & Processing

Scott Butler - mRNA Polyadenylation
Clara Kielkopf - Disease-Associated pre-mRNA Recognition
Lynne Maquat - RNA Decay Pathways
David Mathews - RNA Secondary Structure Prediction
Eric Phizicky - tRNA Modification and Function; Proteome Analysis
Harold Smith - mRNA Editing
Douglas Turner - RNA Folding & Therapeutics
Joseph Wedekind - Crystallography of RNA Editing Enzymes and Ribozymes
Yi-Tao Yu - snRNA Modification

Signal Transduction

Jun-ichi Abe - Signal Transduction in Cardiovascular Disease
Dirk Bohmann - Transcription Control in Development
William Bowers - Inflammation and Alzheimer's Disease
Ian Dickerson - Mechanisms of G Protein Signal Transduction
Mark Dumont - Signaling by G Protein Coupled Receptors
Keigi Fujiwara - Mechano-Signaling and Response by Epithelial Cellsn
Alan Grossfield - nvestigating membranes and membrane proteins via computer simulation
Patricia Hinkle - Peptide Hormone Signaling
Hartmut Land - Signaling Networks in Cancer
Willis Li - Signal Transduction and Epigenetic Regulation
Mahin Maines - Linking Heme Oxygenase to Insulin/MAPK Signaling
Keith Nehrke - Integrative Physiology in C. elegans
Irfan Rahman - NF-kB and Redox Regulation of Cell Signaling
Alan Smrcka - G-Protein Signaling
Yin Sun - TGFb Signaling
Jiyong Zhao - Cell Cycle Regulation