My Contact Information

Professor of Biochemistry and Biophysics
and Medical Informactics
Ph.D. Harvard University 1958

Optical pattern recognition of biological specimans.

Current interest is image processing applied to medical and biological data and application of information handling techniques to medical education. Prior areas of interest have been emission and transmission tomography and ultrasound. Collaborative work has included epidemiology of cancer due to radiation exposure and smoking, sodium and potassium transport and metabolic models of cell differentiation.

Automated identification of cells (left), in a one micron thick plastic section of mouse cerebral cortex (right).

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Recent Publications

Simon W, Segel GB, Lichtman MA (2006) Early allogeneic stem cell transplantation for chronic myelogenous leukemia in the imatinib era: A preliminary assessment. Blood Cells Mol Dis,

Shrager P, Simon W, Kazarinova-Noyes K (2005) Na+ Channel Reorganization in Demyelinated Axons. In Multiple Sclerosis as a Neuronal Disease. Edited by Stephen G. Waxman . Elsevier Academic Press ,

Custer AW, Kazarinova-Noyes K, Sakurai T, Xu X, Simon W, Grumet M, Shrager P (2003) The role of the ankyrin-binding protein NrCAM in node of Ranvier formation. J Neurosci, 23:10032-9

Weiss B, Clarkson TW, Simon W (2002) Silent latency periods in methylmercury poisoning and in neurodegenerative disease. Environ Health Perspect, 110 Suppl 5:851-4

Morsch R, Simon W, Coleman PD (1999) Neurons may live for decades with neurofibrillary tangles. J Neuropathol Exp Neurol, 58:188-97

Simon W (1998) A simple stereoscopic endoscope. Jsls, 2:67-70

Maillie DH, Simon W (1995) A method of estimating the loss of life expectancy from lifetime exposure to low dose rate radiation. Journal of the Franklin Institute, 332A:93-100

Maillie DH, Simon W, Greenspan BS, Watts RJ, Quinn BR (1994) The influence of life table corrections for smokers and nonsmokers on the health effects of radon using the BEIR IV method. Health Physics, 66:615-620

Maillie HD, Simon W, Watts RJ, Quinn BR (1993) Determining person-years of life lost using the BEIR V method. Health Phys, 64:461-6

Spar I, Simon W, Pryor KC (1993) The effect of debt level on the residency preferences of graduating medical students. Academic Medicine,, 68:570-572

Simon W, Segel GB, Lichtman MA (1988) Upper and lower time limits in the decision to recommend marrow transplantation for patients with chronic myelogenous leukaemia. Br J Haematol, 70:31-6

Simon W (1988) Anatomy helper: computer-assisted anatomy instruction. Comput Methods Programs Biomed, 26:71-4

Simon W (1976) Appendix In: Postassium transport in human blood lymphocytes treated with phytohemagglutinin by Segel, G.B. and Lichtman. M.A., Journal of Clinical Investigation, 58:1558

Simon W (1970) A method of exponential separation applicable to small computers. Phys Med Biol, 15:355-60

Tretiak OJ, Eden M, Simon W (1969) Pattern recognition and image processing: Internal structure from X-ray images. International Conference on Engineering in Medicine and Biology, Chicago,

Wright B, Simon W, Walsh BT (1968) A kinetic model of metabolism essential to differentiation in Dictyostelium discoideum. Proc Natl Acad Sci U S A, 60:644-51

Contact Information

E-Mail: William_Simon@urmc.rochester.edu

William Simon
Department of Biochemistry and Biophysics
University of Rochester School of Medicine and Dentistry
601 Elmwood Ave, Box 712
Rochester, New York 14642

Office: Medical Center Annex C-15
Telephone: (585) 275-3034; Fax: (585) 275-6007