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in the University of Rochester's Department of Biochemistry & Biophysics
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Graduate Programs
The Department of Biochemistry and Biophysics administers two Ph.D. programs, a Ph.D. program in Biochemistry and a Ph.D. program in Biophysics. Entry into these programs is typically through their associated clusters, the Biochemistry, Molecular and Cell Biology Cluster for the Ph.D. in Biochemistry and the Biophysics and Structural Biology Cluster for the Ph.D. in Biophysics. Note that the clusters allow students greater flexibility in their choice of advisor and program. More information can be found via the links to the cluster websites below.
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For the Biochemistry program,
visit the BMCB site.
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For the Biophysics and Structural
Biology program, visit the
BSB program site
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A Message from the Department Faculty
Biomedical sciences are currently experiencing a golden era, founded on recent advances in molecular biology, biophysics, structural biology and biochemistry. Almost daily we learn of discoveries that impact our understanding of human diseases. We are on the threshold of defining the exact molecular mechanisms of genetic diseases, carcinogenesis, development, aging, and many cellular processes. Our department provides students and postdoctoral fellows a program aimed at understanding fundamental mechanisms and the structural basis of life processes. We believe that the next decade of science will rely on a blend of structural biology, molecular biology, and molecular genetics. Faculty in our department integrate these fields on topics that span from regulation of gene expression, recombination and chromatin structure, to cell signaling, cell cycle control, membrane biology, RNA and protein structure and function, and receptor-ligand or enzyme-substrate interactions. We utilize prokaryotic, yeast, nematode and mammalian model systems and incorporate advanced genomics and proteomics approaches of study. The physics and chemistry of biomacromolecules is studied using x-ray crystallography, NMR spectroscopy, EPR and ENDOR spectroscopy, fluorescence transfer, CD, and a variety of chromatographic techniques.
The Department of Biochemistry and Biophysics is comprised of over 40 faculty with well-
funded and active research programs in many diverse areas. Our graduate education programs are affiliated with other departments, including Biology, Chemistry, Immunology , Microbiology and Vaccine Biology, and Cancer Biology. Graduate students in our Ph.D. programs, therefore, have a great deal of flexibility to rotate through many different types of research labs. A significant priority of the faculty in our department is to provide a high quality, dynamic, and very supportive research and teaching environment for graduate students. While we have 39 individual research labs, many research groups in our department interact very successfully and build strengths and expertise in eight main research areas, which are valuable to the training of graduate students and postdoctoral fellows.
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Genomics, Proteomics and Model Systems for Development
Cell Signaling
Membrane Biology
Cell Cycle and Cancer
Chromatin Structure, Gene Regulation and Repair
RNA Processing
Protein Structure and Function
Molecular Biophysics
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Twenty five faculty members in our department are affiliated with two main graduate education programs.
Biophysics and Structural Biology faculty mentor graduate students working toward a Ph.D. in Biophysics (See faculty list).
Biochemistry, Molecular and Cell Biology faculty mentor graduate students working toward a Ph.D. in Biochemistry (See faculty list ).
At present, we have 30 Ph.D. graduate students in Biophysics and 55 Ph.D. graduate students in Biochemistry. Please view their annual student research seminar presentation list.
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In their first year of graduate school, students rotate through three to four research labs. By the end of their first year, they select a faculty member for their thesis advisor (see Faculty Mentor page) and they devise a research topic for their Ph.D. thesis. Most coursework is completed by the first year; however, advanced courses in selected research areas are also available in subsequent years.
By the second year students, focus on a research project, receive more advanced research training, assemble a thesis advisory committee and complete a qualifying exam.
For more detailed information on the graduate education programs, visit the individual graduate program web sites:
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Click here to Apply to graduate school.
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Click here for the current student handbook for BIOPHYSICS students.
Click here for FIRST YEAR REQUIREMENTS for BIOCHEMISTRY students.
Click here for the current student handbook for BIOCHEMISTRY students.
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